The 21-year-old shimmered in Giorgio Armani number, which attracted attention thanks to the bow detail. Nicki Minaj and Little Mix joined forces for an empowering performance of their collaboration "Woman Like Me".
Minaj was in contrast to the girls' black and white attire with a glittery embroidered and sequin-embellished pink bodysuit.
Her album "Camila" also reached the top of U.S. charts in January, and the audio version of "Havana", which features rapper Young Thug, has had more than 1.3 billion hits on YouTube.
She told the Press Association: "I think that it's always been hard".
"I feel moved to speak for women's voices who have been stifled", she said.
"Women who have been gagged". Women who have been abused, women who have been intimidated, women who live in fear... Women who have been intimated.
This year's show also awarded the first-ever "MTV EMA Generation Change Award" to elevate and empower the fearless, original young people who are changing the world.
In his acceptance speech, the sister of Michael Jackson said, speaking in the name "of those women whose voices have been silenced". We have a long long way to go and trust me, we wouldn't have been able to do this without you.