He's been named to the NBA All-Defensive First Team three years in a row, from 2015-2017.
But will the Rockets star finally take home the top league honor?
Harden led the National Basketball Association in scoring at 30.4 points per game, while guiding the Rockets to a franchise-best 65 wins.
At 33, James would be the oldest player to win the award since 35-year-old Karl Malone did so in 1998-99.
While Mitchell did average more points in the regular season, Simmons averaged more rebounds, assists, steals and played more effective defense than his opponent over the first 91 games of his National Basketball Association career and looks like a potential superstar.
Houston's James Harden, Cleveland's LeBron James and Anthony Davis of New Orleans are the finalists for the NBA's Most Valuable Player award. Harden and James are now playing in their conference finals.
He could join Bill Russell and Michael Jordan as 5-time MVP winners.
The finalists were based on voting results from a global panel of sportswriters and broadcasters.
Harden is the frontrunner for the award as he has been the Houston Rockets' best player as they finished not only as the No. 1 seed in the Western Conference over the Golden State Warriors but as the best team in the regular season overall with an impressive 65-17 record.
After plenty of off-court chat, Donovan Mitchell and Ben Simmons will continue their battle for rookie of the year, while Jayson Tatum is also a finalist.
Davis averaged a career-best 28.1 points to go with 11.1 rebounds and 2.6 blocks and is also a finalist for Defensive Player of the Year along with Rudy Gobert of the Utah Jazz and Joel Embiid of the Philadelphia 76ers.