"The Syrian air defense system has been conducting an anti-air fight", the ministry added.
The Russian defence ministry was quoted as saying that Syria deployed Russian-made surface-to-air missiles, including S-125, S-200, 2K12 Kub and Buk to repel the attacks.
He said Russian air defences did not fire, while Syrian air defences were completely ineffective against an attack from multiple directions involving not just US, British and French aircraft but also US naval destroyers, a cruiser, a French frigate and even a US submarine.
Among those targeted by the US-led operation was the Al-Dumayr military airport outside of Damascus.
Marine Lt Gen Kenneth McKenzie, director of the Joint Staff, rejected assertions from Russian Federation and Syria that scores of the Western missiles were shot down.
Syrian air defenses were scrambled to confront the joint American-French-British intervention that started in the early hours of Saturday.
The US, the United Kingdom and France said the strikes were in response to an alleged chemical weapons attack in Douma, a suburb of Syria's capital. The strikes were announced before a team of investigators from the Organization for the Prohibition of Chemical Weapons (OPCW) was scheduled to reach Douma to determine whether the attack had indeed taken place.