I wouldn't trade any of it.
Having begun working together in 2001, Roach and Pacquiao would embark on a decade that would see the Filipino fighter named the best fighter of the 2000's by both the WBC and WBO.
Roach said he wished Pacquiao well for the future but had been "hurt" after learning of the Filipino's decision to axe him indirectly.
Roach first cornered Pacquiao in his maiden voyage to the United States opposite South Africa's Lehlo Ledwaba in June 2001, a fight Pacquiao won by sixth-round TKO.
"I would be lying if I didn't say I wasn't hurt that he didn't contact me personally about his decision, but the great times we enjoyed together far outweigh that", said Roach, who was in Pacquiao's corner 32 times, including 28 in the U.S., twice in Macau and once each in Manila and Australia.
"I would be lying if I didn't say I wasn't hurt that he didn't contact me personally about his decision, but the great times we enjoyed together far outweigh that", Roach added.
Manny Pacquiao is no longer under the guidance of Freddie Roach.
All in all, the 16 years of Roach and Pacquiao oversaw 34 fights that led to unprecedented success - but it has finally come to an end.
Pacquiao is to fight Matthysse for the Argentine's WBA welterweight belt in Kuala Lumpur on July 15.
But Pacquiao, who is also a senator in the Philippines, is determined to extend his career.
"Pacquiao will be joined by his new promotions team along with trainers Restituto "Buboy" Fernandez and Raides "Nonoy" Neri", the press release read.
Roach is widely considered one of the greatest trainers in recent boxing history.
Pacquiao is also set to welcome Golden Boy president Oscar Dela Hoya, Matthysse's promoter. Top Rank, Pacquiao's longtime promoter, will handle certain aspects of the promotion.